Combo of bad cholesterol and high blood pressure may increase heart attack or...
A new study suggests lipoprotein(a) cholesterol may affect relationship between hypertension and cardiovascular disease risk.
View ArticleHigh doses of statins increase osteoporosis risk, shows study in animals
An animal experiment demonstrates what big data analysis previously indicated: high doses of statins likely increase osteoporosis risk.
View ArticleSchool garden-based interventions can improve blood sugar, reduce 'bad'...
School garden-based interventions can improve metabolic parameters such as blood sugar and cholesterol in children, according to a new study.
View ArticleBetter understanding cancer and heart disease
A team of researchers has finally identified the molecular mechanism by which a key protein regulates LDL cholesterol.
View ArticleA soybean protein blocks LDL cholesterol production, reducing risks of...
Soybean varieties with greater proportions of the protein B-conglycinin reduce plasma cholesterol levels and promote liver homeostasis, showing potential for preventing fatty liver disease and...
View ArticleBody phenotypes say a lot, but not everything, about a person's health
Researchers studying body phenotypes -- the observable characteristics like height, behavior, appearance and more measurables -- found that regardless of the muscle they had, high levels of fat mass in...
View ArticleStudy finds 1-in-5 patients at high risk of cardiovascular disease refuse...
The study found that in patients at high risk of developing cardiovascular disease, over 20 percent refused to take statin medications. Women were about 20% more likely than men to refuse statin...
View ArticleResearchers discover way to reverse infertility by reducing HDL cholesterol
Scientists reversed infertility in sterile mice by reducing HDL cholesterol with a bacterial protein in a promising development that shows further evidence linking high cholesterol to female...
View ArticleSweets change our brain
Chocolate bars, chips and fries - why can't we just ignore them in the supermarket? Researchers have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even...
View ArticleShedding pounds may benefit your heart -- even if some weight is regained
Weight loss was associated with decreased risk factors for cardiovascular disease and Type 2 diabetes for at least five years -- even if some weight was regained, according to a review of research on...
View ArticleLipid molecules help to get stroke therapies into the brain
Researchers have found that a promising stroke therapy, known as antisense oligonucleotides, is preferentially taken up from the blood into areas of stroke damage in the brain when the molecules are...
View ArticleArterial stiffness may cause metabolic syndrome in adolescents via an...
Arterial stiffness may be a novel risk factor for metabolic syndrome in teens.
View ArticleBehavior patterns of people who achieve clinically significant weight loss
A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk -- while associating skipping meals and taking...
View ArticleGutless marine worms on a Mediterranean diet: Animals can synthesize...
Phytosterols are good for your health, but humans and other animals are not able to make them themselves, only plants can. To acquire phytosterols, humans are increasingly turning to supplements, green...
View ArticleCT scan best at predicting heart disease risk in middle age
CT scans are better at predicting a middle-aged person's risk for a heart disease, such as a heart attack, than genetics, reports a new study. Conventional measures of risk factor levels include blood...
View ArticleFluctuating levels of cholesterol and triglycerides linked to increased risk...
Older people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and related dementias compared to people who have steady levels, according to new...
View ArticleHow a genetic mutation can cause individuals with normal cholesterol levels...
A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery...
View ArticleOne pill doesn't fit all: Cholesterol study reveals effects on lung function...
One of the world's largest studies on the impact of cholesterol-lowering medication has good and bad news for the 200 million people who take statins or other medication for high cholesterol.
View ArticleInsect protein slows weight gain, boosts health status in obese mice
A new study in mice suggests replacing traditional protein sources with mealworms in high-fat diets could slow weight gain, improve immune response, reduce inflammation, enhance energy metabolism, and...
View Article'Humanized' liver in mice reveals roots of chronic diseases
Researchers have created a functional 'humanized' liver in living mice that will help scientists find human-specific mechanisms for regulating cholesterol levels and potentially for treating chronic...
View ArticleDrug to target form of previously untreatable life-threatening 'bad cholesterol'
New research details the first oral drug for the treatment of a type of high cholesterol -- called Lp(a) -- that is a potentially more dangerous version of the so called 'bad' cholesterol, LDL, because...
View ArticleEnhancing immune defenses: Researchers unveil the secrets of specialized T...
Immunologists have uncovered new approaches to enhance protection from tumors and infections. They have revealed new insights into the metabolism of specialized cells of the immune system known as...
View ArticleCan taking statins after a bleeding stroke lower risk of another stroke?
People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared...
View ArticleUncovering how our cells process cholesterol
Scientists have found how human cells distribute and maintain their cholesterol levels, aiding in research in neurodegenerative diseases such as Alzheimer's disease, as well as cardiovascular diseases.
View ArticleSwap red meat for Quorn protein to improve heart health and reduce waist...
People looking to reduce their cholesterol and trim fat from around their waist could try swapping meat for Quorn protein, according to the findings from a new study, which saw positive effects in both...
View ArticleProtein that could help defeat Alzheimer's and increase productive lifespan
Alzheimer’s disease is the most common type of dementia, a disorder of progressively worsening memory and other thinking abilities. It rose up in the ranks of leading causes of death over the past...
View ArticleResearchers uncover mechanism for treating dangerous liver condition
A study has shown why certain polyunsaturated fatty acids work to combat a dangerous liver condition, opening a new avenue of drug research for a disease that currently has no FDA-approved medications.
View ArticleHigher levels of triglycerides linked to lower risk of dementia
Older people who have higher levels of triglycerides, a type of fat, may have a lower risk of dementia and a slower cognitive decline over time compared to people who have lower levels, according to...
View ArticleResearchers identify previously unknown step in cholesterol absorption in the...
UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream -- potentially...
View ArticleGround-breaking discovery could pave the way for new therapies to prevent...
Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol...
View ArticleNew medication given every 1-3 months may slash stubborn high cholesterol
While currently available PCSK9 inhibitor medications to lower cholesterol must be administered every few weeks by injection, a new, investigational PCSK9 inhibitor called recaticimab safely lowered...
View ArticleAppropriate statin prescriptions increase sixfold with automated referrals
The odds of prescribing the appropriate dose of statins -- a medicine used to lower 'bad' cholesterol levels -- increased sixfold when automated referrals were made to pharmacy services, instead of...
View ArticleLowering a form of brain cholesterol reduces Alzheimer's-like damage in mice
Researchers have found that a form of cholesterol known as cholesteryl esters builds up in the brains of mice with Alzheimer's-like disease, and that clearing out the cholesteryl esters helps prevent...
View ArticleVery high levels of 'good cholesterol' may be associated with dementia risk:...
Abnormally high levels of HDL-C, colloquially known as 'good cholesterol', are associated with an increased risk of dementia in older adults.
View ArticleCholesterol-lowering therapy may hinder aggressive type of colorectal tumor
Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a...
View ArticleScientists enhance cell-based therapy to destroy solid tumors
Researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells -- an approach known as 'cell-based therapy,' which uses specially...
View ArticleHigh cholesterol caused by childhood sedentariness could be reversed with...
Increased sedentary time in childhood can raise cholesterol levels by two thirds as an adult, leading to heart problems and even premature death -- but a new study has found light physical activity may...
View ArticleScientists use organoid model to identify potential new pancreatic cancer...
A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments.
View ArticleA novel pathway regulating lipid biosynthesis by fatty acids
Sterol regulatory element-binding proteins (SREBPs) play a crucial role in lipid biosynthesis. In a recent study, researchers identified a novel cleavage enzyme of SREBP-1c, a key player in fatty acid...
View ArticlePrecursor of cholesterol protects cells from ferroptosis
A precursor of cholesterol, previously categorized as harmful, can protect cancer cells from cell death.
View ArticleScientists uncover a crucial link between cholesterol synthesis and cancer...
A study has found an important connection between cancer, stem cells and the building blocks of cholesterol. Specifically, the research reveals how the enzyme FAXDC2 influences cancer cell growth and...
View ArticleLink between high levels of niacin -- a common B vitamin -- and heart...
Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team...
View ArticleCommon hair loss and prostate drug may also cut heart disease risk in men and...
The drug finasteride, also known as Propecia or Proscar, treats male pattern baldness and enlarged prostate in millions of men worldwide. But a new study suggests the drug may also provide a surprising...
View ArticleMore than half of American Indian youth may have abnormal or high cholesterol
More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovascular disease, a new...
View ArticleThe liver immune system eats up 'bad cholesterol'
A new study reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries. The findings suggest that the response to...
View ArticleEggs may not be bad for your heart after all
Whether you like your eggs sunny-side up, hard boiled or scrambled, many hesitate to eat them amid concerns that eggs may raise cholesterol levels and be bad for heart health. However, results from a...
View ArticleFor younger women, mental health now may predict heart health later
Younger women are generally thought to have a low risk of heart disease, but new research urges clinicians to revisit that assumption, especially for women who suffer from certain mental health...
View ArticlePotential treatment targets for Zika virus-related eye abnormalities
A groundbreaking study presents crucial insights into the ocular effects of Zika virus infection during pregnancy and offers promising avenues for therapeutic intervention.
View ArticleScientists link certain gut bacteria to lower heart disease risk
Changes in the gut microbiome have been implicated in a range of diseases including type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers has found that microbes in the...
View ArticleResearchers discover how we perceive bitter taste
A new study reveals the detailed protein structure of the TAS2R14, a bitter taste receptor that allows us to perceive bitter taste. In addition to solving the structure of this taste receptor, the...
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